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Title   국소 및 영역 임파절에서 재발한 유암의 치료 - 방사선치료 단독과 항암제와의 병행요법의 비교 분석 - ( Management of Locoregiona Recurrent Breast Cancer )
Publicationinfo   1992 Jan; 024(05): 684-695.
Key_word   Breast cancer, Local-regional recurrence
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Abstract   To evaluate the influence of radiation or radiation and chemotherapy on locoregional tumor control and survival, 40 patients with recurrent breast cancer after mastectomy treated between January l980 and June 1986 at the Yonsei Cancer Center were retrospectively analysed. Treatment consisted of radiation alone in 23 patients and a combination of radiation and chemotherapy in the other 17 patients. The patient characteristics of these two groups are comparable. All patients treated with radical irradiation received 4500 cGy with generous field of involved site or prophylactic irradiation to chest wall and peripheral lymphatics. Locoregional control was achieved in 81% of all patients. Optimal locoregional control was achieved with radical radiation therapy. Distant metastasis was developed in 43.2% of all patients. Five year survival and 5-year disease free survival is 53.3/ and 37.4%, respectively. The addition of chemotherapy is not beneficial in terms of improving locoregional control and survival rate, or reducing distant metastasis. The prognostic factor affecting survival is disease free interval between mastectomy and recurrence.
저 자   박경란(Kyung Ran Park),이종영(Jong Young Lee),이창걸(Chang Ok Suh),서창옥(Chang Ok Suh),노준규(Jun Kyu Loh),김귀언(Gwi Eon Kim),김수곤(Soo Kon Kim),오원용(Won Yong Oh),고은희(Eun Hee Koh),김병수(Byung Soo Kim)